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"George Clooney has been named PEOPLE's Sexiest Man Alive for 2006 – joining his pal Pitt as a two-time honoree.

"Brad's going to be upset," the 45-year-old Oscar winner tells PEOPLE in its special issue.

Then again, after the year Clooney's had, his buddy will understand. Hollywood's consummate gentleman kicked things off with an Academy Award (winning Best Supporting Actor for Syriana,) and Clooney further cemented his reputation for social activism, working on behalf of causes to help the troubled Darfur region of Sudan."
PEOPLE

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